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1 article(s) from Ünal, Sedat

Insight into oral amphiphilic cyclodextrin nanoparticles for colorectal cancer: comprehensive mathematical model of drug release kinetic studies and antitumoral efficacy in 3D spheroid colon tumors

Sedat Ünal,
Gamze Varan,
Juan M. Benito,
Yeşim Aktaş and
Erem Bilensoy

Beilstein J. Org. Chem. 2023, 19, 139–157, doi:10.3762/bjoc.19.14

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Graphical Abstract

Figure 1: In vitro release profile of CPT from nanoparticle formulations (n = 3, ± SD).

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Figure 2: Results for release kinetics obtained automatically by the DDSolver software for SGF release medium...

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Figure 3: Results for release kinetics obtained automatically by the DDSolver software for SIF release medium...

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Figure 4: Results for release kinetics obtained automatically by the DDSolver software for SCoF release mediu...

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Figure 5: Anticancer effect of blank or CPT-loaded CD nanoparticles and camptothecin solution against 2D CT26...

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Figure 6: Live/dead analysis of CT26 and HT29 cells using double staining with calcein AM and ethidium homodi...

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Figure 7: Murine (CT26) and human (HT29) colon cancer spheroid was formed by scaffold-based method, and the m...

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Figure 8: Anticancer effect of blank or drug-loaded cyclodextrin nanoparticles and CPT solution against 3D CT...

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Figure 9: Chemical structures of 6-O-capro-β-CD, poly-β-CD-C6, and chitosan.

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Published 13 Feb 2023

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